Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.57 |
| ▸ | RAD52 | P43351 | 4/20 | 0.57 |
| ▸ | KIF11 | P52732 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 8/20 | 0.52 |
| ▸ | HTR2A | P28223 | 6/20 | 0.52 |
| ▸ | HRH1 | P35367 | 6/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.52 |
| ▸ | HTR2C | P28335 | 5/20 | 0.52 |
| ▸ | DRD3 | P35462 | 5/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.52 |
| ▸ | HTR2B | P41595 | 4/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.52 |
| ▸ | DRD1 | P21728 | 3/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.52 |
| ▸ | HTR6 | P50406 | 3/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237819 | 0.84 | CYP2D6 (0.63) | CYP2D6RAD52KIF11DRD2HTR2A | |
| SCHEMBL11743885 | 0.77 | DRD2 (0.73) | CYP2D6RAD52DRD2HTR2AHRH1 | |
| SCHEMBL11244507 | 0.77 | CYP2D6 (0.85) | CYP2D6RAD52KIF11DRD2HTR2A | |
| SCHEMBL4444154 | 0.77 | CYP2D6 (0.85) | CYP2D6RAD52KIF11DRD2HTR2A | |
| SCHEMBL11246700 | 0.77 | CYP2D6 (0.67) | CYP2D6RAD52KIF11DRD2HTR2A | |
| Hydrochloric Acid SCHEMBL11749117 | 0.76 | DRD2 (0.71) | CYP2D6RAD52DRD2HTR2AHRH1 | |
| SCHEMBL11237816 | 0.74 | CYP2D6 (0.61) | CYP2D6RAD52KIF11DRD2HTR2A | |
| SCHEMBL8869747 | 0.71 | LMNA (0.64) | CYP2D6RAD52DRD2HTR2AHRH1 | |
| SCHEMBL10480940 | 0.70 | CYP2D6 (0.62) | CYP2D6RAD52KIF11DRD2HTR2A | |
| SCHEMBL11236719 | 0.70 | DRD2 (0.53) | CYP2D6DRD2HTR2AHRH1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366154-A | TRANQUILIZERS; PSYCHOLOGICAL DISORDERS | SANDOZ, INC. (US) | 1982-12-28 | — | — | US | claimed |