Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973187 | 0.74 | GRM6 (0.40) | — | |
| SCHEMBL3546569 | 0.64 | HSD11B1 (0.40) | GRIN2BHSD11B1 | |
| SCHEMBL2818160 | 0.64 | HSD11B1 (0.40) | GRIN2BHSD11B1 | |
| SCHEMBL12350687 | 0.62 | HSD11B1 (0.46) | P2RX7PKMHSD11B1TP53SMN1; SMN2 | |
| SCHEMBL22982286 | 0.60 | EPHX1 (0.39) | OPRK1CHRM2CHRM1CHRM3 | |
| SCHEMBL5506656 | 0.60 | CYP2C19 (0.44) | NPC1POLBSMN1; SMN2KDM4ECYP2C19 | |
| SCHEMBL11748541 | 0.60 | LMNA (0.48) | RAB9ANPC1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL6997763 | 0.59 | P2RX7 (0.43) | P2RX7GRIN2BHSD11B1SMN1; SMN2KDM4E | |
| SCHEMBL6990253 | 0.59 | P2RX7 (0.43) | P2RX7GRIN2BHSD11B1SMN1; SMN2KDM4E | |
| SCHEMBL23137098 | 0.59 | CTSK (0.42) | CYP2D6CHRM1RAB9ANPC1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57197262-A | — | — | None | — | — | JP | disclosed |
| JP-S57197262-A | PRODUCTION OF OPTICALLY ACTIVE BETA-ARYLTHIO OR ALKYLTHIOKETONE | RES DEV CORP OF JAPAN | 1982-12-03 | — | — | JP | disclosed |