Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.39 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.39 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780678 | 0.79 | SLC6A1 (0.56) | SIGMAR1POLBSLC6A1SLC6A12SLC6A11 | |
| SCHEMBL11252330 | 0.76 | SLC6A1 (0.49) | SLC6A1SLC6A12SLC6A11CHRM2CHRM1 | |
| SCHEMBL11245908 | 0.74 | SLC6A1 (0.45) | USP2SLC6A1SLC6A12SLC6A11KDM4E | |
| Fumaric Acid SCHEMBL11262713 | 0.71 | ALDH1A1 (0.41) | SIGMAR1SLC6A1SLC6A12SLC6A11BCHE | |
| SCHEMBL7782410 | 0.69 | SLC6A1 (0.46) | SLC6A1SLC6A12SLC6A11CHRM1HTR2A | |
| SCHEMBL14028115 | 0.68 | LTA4H (0.46) | SIGMAR1POLBKDM4EACHEALDH1A1 | |
| SCHEMBL11247019 | 0.67 | CXCR3 (0.41) | SIGMAR1POLBKDM4EACHEALDH1A1 | |
| SCHEMBL11262967 | 0.66 | SLC6A1 (0.53) | SLC6A1SLC6A12SLC6A11CYP1A2HRH3 | |
| SCHEMBL13503692 | 0.65 | OPRM1 (0.45) | SIGMAR1POLBKDM4EALDH1A1CYP1A2 | |
| SCHEMBL11251634 | 0.64 | SLC6A1 (0.43) | POLBSLC6A1SLC6A12SLC6A11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342762-A | USEFUL AS TRANQUILIZERS, ANALGESICS, ANTIEPILEPTIC AGENTS, AND AS A TREATMENT FOR PARKINSON'S DISEASE | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1982-08-03 | — | — | US | disclosed |