Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29937640 | 1.00 | PYCR1 (0.49) | PYCR1KDM4ETDP1ERN1MEN1 | |
| SCHEMBL6044488 | 0.85 | KDM4E (0.53) | KDM4ETDP1MEN1USP2ALDH1A1 | |
| SCHEMBL30223764 | 0.85 | PYCR1 (0.51) | PYCR1KDM4ETDP1MEN1USP2 | |
| SCHEMBL1427602 | 0.85 | PYCR1 (0.51) | PYCR1KDM4ETDP1MEN1USP2 | |
| SCHEMBL3484619 | 0.83 | PYCR1 (0.50) | PYCR1KDM4ETDP1HTR2A | |
| SCHEMBL3858881 | 0.82 | TSHR (0.46) | TDP1MEN1ALDH1A1GAAMAPT | |
| SCHEMBL1569750 | 0.81 | TAAR1 (0.61) | HTR2AHTR2CTAAR1 | |
| SCHEMBL27488871 | 0.81 | PYCR1 (0.49) | PYCR1KDM4ETDP1MEN1USP2 | |
| SCHEMBL1446144 | 0.80 | PYCR1 (0.48) | PYCR1KDM4ETDP1HTR2A | |
| SCHEMBL20562481 | 0.80 | POLB (0.53) | PYCR1KDM4ETDP1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12503452-B2 | Antimicrobial compounds and methods | CURZA GLOBAL, LLC (US) | 2025-12-23 | — | — | US | disclosed |
| US-20250213700-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR CELL-SPECIFIC PHARMACOLOGY | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. | 2025-07-03 | — | — | US | disclosed |
| CN-113574058-B | Indole macrocyclic derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-04-16 | — | — | CN | disclosed |
| WO-2023225369-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR CELL-SPECIFIC PHARMACOLOGY | DUKE UNIVERSITY (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023225369-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR CELL-SPECIFIC PHARMACOLOGY | DUKE UNIVERSITY (US) | 2023-11-23 | — | — | WO | disclosed |
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
| US-20230072397-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-03-09 | — | — | US | disclosed |
| US-20220041623-A1 | INDOLE MACROCYCLIC DERIVATIVE, PREPARATION METHOD THEREOF AND APPLICATION THEREOF IN MEDICINE | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2022-02-10 | — | — | US | disclosed |
| CN-113924292-A | Antimicrobial compounds and methods | 库扎环球有限责任公司 | 2022-01-11 | — | — | CN | disclosed |
| CN-113825748-A | Antimicrobial compounds and methods | 库扎环球有限责任公司 | 2021-12-21 | — | — | CN | disclosed |
| US-20130197217-A1 | 1, 2, 4-TRIAZOLONE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2013-08-01 | — | — | US | disclosed |
| US-20120202777-A1 | C-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents | BROWN MATTHEW FRANK (US) | 2012-08-09 | — | — | US | disclosed |
| US-20120202777-A1 | C-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents | BROWN MATTHEW FRANK (US) | 2012-08-09 | — | — | US | disclosed |
| US-20120202777-A1 | C-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents | BROWN MATTHEW FRANK (US) | 2012-08-09 | — | — | US | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |
| WO-2008079836-A2 | MACROCYCLIC FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-07-03 | — | — | WO | disclosed |
| CN-1173974-C | Piperidylaminomethyltrifluoromethyl cyclic ether compound as p substance antagonist | ������ҩ������˾ | 2004-11-03 | — | — | CN | disclosed |
| CN-1140525-C | 1-trifluoromethyl-4-hydroxy-7-piperidinyl-aminomethylchroman derivatives | �Ʒ� | 2004-03-03 | — | — | CN | disclosed |
| CN-1355799-A | 1-trifluoromethyl-4-hydroxy-7-piperidinyl-aminomethylchroman derivatives | PFIZER PROD INC (US) | 2002-06-26 | — | — | CN | disclosed |
| CN-1279681-A | Piperidinylaminomethyltrifluoromethyl cyclic ether compounds as substance P antagonists | PFIZER (US) | 2001-01-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | PYCR1 2907/4885KDM4E 3027/4885TDP1 4219/4885 |
| US-20120202777-A1 | C-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents | HAX1, LPXN, AGXT | PYCR1 1015/4885KDM4E 1331/4885TDP1 2637/4885 |
| US-20130197217-A1 | 1, 2, 4-TRIAZOLONE DERIVATIVE | AVPR1B, AVPR1A, AVPR2 | PYCR1 602/4885KDM4E 2260/4885TDP1 707/4885 |
| US-20250213700-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR CELL-SPECIFIC PHARMACOLOGY | DDT, ABCG2, CES2 | PYCR1 1574/4885KDM4E 2188/4885TDP1 1046/4885 |
| US-20230072397-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | PYCR1 2907/4885KDM4E 3027/4885TDP1 4219/4885 |
| US-20220041623-A1 | INDOLE MACROCYCLIC DERIVATIVE, PREPARATION METHOD THEREOF AND APPLICATION THEREOF IN MEDICINE | MCL1, IDO1, TPH1 | PYCR1 187/4885KDM4E 1996/4885TDP1 2045/4885 |
| US-12503452-B2 | Antimicrobial compounds and methods | MPO, NISCH, RPN2 | PYCR1 2907/4885KDM4E 3027/4885TDP1 4219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.