Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237839 | 0.83 | MAPT (0.40) | MTNR1AMTNR1BTSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11236943 | 0.82 | MAPT (0.39) | MTNR1AMTNR1BTSHRMEN1KMT2A | |
| SCHEMBL11234640 | 0.82 | MEN1 (0.46) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11230532 | 0.82 | MAPT (0.46) | SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11230239 | 0.79 | ALDH1A1 (0.46) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11246090 | 0.79 | MAPT (0.50) | RAB9ANPC1SMN1; SMN2MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL11247369 | 0.78 | ALDH1A1 (0.45) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11240133 | 0.76 | CTSK (0.49) | RAB9ANPC1ALDH1A1MAPTCASR | |
| SCHEMBL11244735 | 0.75 | TSHR (0.36) | SMN1; SMN2MTNR1AMTNR1BTSHRKMT2A | |
| SCHEMBL11233874 | 0.75 | SLC6A4 (0.39) | RAB9ANPC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |