⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10240204 | 0.75 | ALDH1A1 (0.33) | — | |
| SCHEMBL11076123 | 0.74 | — | — | |
| SCHEMBL11247305 | 0.74 | KMT2A (0.62) | — | |
| SCHEMBL10189375 | 0.74 | GHSR (0.33) | — | |
| SCHEMBL95236 | 0.72 | — | — | |
| SCHEMBL31518320 | 0.71 | ALDH1A1 (0.50) | — | |
| SCHEMBL11247291 | 0.69 | LMNA (0.38) | — | |
| SCHEMBL11116878 | 0.67 | ALDH1A1 (0.42) | — | |
| SCHEMBL15186990 | 0.67 | — | — | |
| SCHEMBL4403686 | 0.67 | MAPK1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622464-B2 | Morpholinyl-urea derivatives for use in the treatment of inflammatory diseases | GLAXO GROUP LIMITED (GB) | 2009-11-24 | — | — | US | disclosed |
| EP-1487828-B1 | MORPHOLINYL-UREA DERIVATIVES FOR USE OF THE TREATMENT OF INFLAMATORY DISEASES | GLAXO GROUP LTD (GB) | 2008-11-05 | — | — | EP | disclosed |