Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11247305 | 0.78 | KMT2A (0.62) | ALDH1A1KMT2ALMNAMEN1MAPT | |
| SCHEMBL11247291 | 0.78 | LMNA (0.38) | ALDH1A1KMT2ALMNA | |
| SCHEMBL11118026 | 0.71 | KMT2A (0.44) | ALDH1A1KMT2ALMNAHSD17B10CYP2C19 | |
| SCHEMBL11076123 | 0.67 | — | — | |
| SCHEMBL8445215 | 0.67 | — | — | |
| SCHEMBL13638133 | 0.67 | — | — | |
| SCHEMBL10189375 | 0.63 | GHSR (0.33) | KMT2ALMNA | |
| SCHEMBL9547313 | 0.59 | ALDH1A1 (0.62) | ALDH1A1KMT2ALMNAHSD17B10KDM4E | |
| SCHEMBL10971800 | 0.55 | ALDH1A1 (0.55) | ALDH1A1KMT2ALMNAHSD17B10KDM4E | |
| SCHEMBL6897277 | 0.55 | ALDH1A1 (0.61) | ALDH1A1KMT2ALMNAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127847-A1 | 7-Oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1984-12-12 | — | — | EP | disclosed |