Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 4/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15716423 | 0.83 | PDE2A (0.42) | LMNAALDH1A1HTTHPGDTSHR | |
| SCHEMBL7598651 | 0.80 | TSHR (0.47) | LMNAALDH1A1HTTHPGDMAPK1 | |
| SCHEMBL11249549 | 0.78 | CTSS (0.48) | LMNAALDH1A1HTTHPGDMEN1 | |
| SCHEMBL14065364 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KMT2ATSHRCTSSAKR1C3 | |
| SCHEMBL11639107 | 0.77 | TSHR (0.44) | LMNAALDH1A1HTTHPGDTSHR | |
| SCHEMBL8358267 | 0.77 | HPGDS (0.49) | LMNAALDH1A1HTTHPGDMEN1 | |
| SCHEMBL11256931 | 0.77 | ALDH1A1 (0.54) | LMNAALDH1A1HTTMAPTKMT2A | |
| SCHEMBL9848415 | 0.76 | LMNA (0.53) | LMNAALDH1A1HPGDCTSSSMN1; SMN2 | |
| SCHEMBL15716728 | 0.75 | CTSS (0.51) | ALDH1A1MEN1MAPTKMT2ATSHR | |
| SCHEMBL7932238 | 0.73 | CTSS (0.42) | LMNAALDH1A1TSHRCTSSAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335053-A | HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1982-06-15 | — | — | US | disclosed |
| US-4288384-A | N-Cyanoalkyl haloacetamides herbicidal antidotes | STAUFFER CHEMICAL COMPANY (US) | 1981-09-08 | — | — | US | disclosed |