Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.48 |
| ▸ | CTSL | P07711 | 4/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15716728 | 0.83 | CTSS (0.51) | CTSSCTSLCTSBCTSKTSHR | |
| SCHEMBL7598651 | 0.82 | TSHR (0.47) | CTSSCTSKTSHRHPGDALDH1A1 | |
| SCHEMBL11256931 | 0.81 | ALDH1A1 (0.54) | CTSSTSHRALDH1A1KMT2AMAPT | |
| SCHEMBL14065364 | 0.79 | ALDH1A1 (0.53) | CTSSCTSKTSHRALDH1A1KMT2A | |
| SCHEMBL11639107 | 0.79 | TSHR (0.44) | CTSSCTSKTSHRHPGDALDH1A1 | |
| SCHEMBL7932238 | 0.78 | CTSS (0.42) | CTSSCTSLCTSBCTSKTSHR | |
| SCHEMBL11247802 | 0.78 | LMNA (0.41) | CTSSCTSLCTSBCTSKTSHR | |
| SCHEMBL12310934 | 0.78 | CTSC (0.48) | CTSSCTSLCTSBCTSKALDH1A1 | |
| SCHEMBL9848415 | 0.77 | LMNA (0.53) | CTSSCTSLCTSBCTSKHPGD | |
| SCHEMBL7867488 | 0.77 | MME (0.43) | CTSSALDH1A1MAPTCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335053-A | HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1982-06-15 | — | — | US | disclosed |
| US-4288384-A | N-Cyanoalkyl haloacetamides herbicidal antidotes | STAUFFER CHEMICAL COMPANY (US) | 1981-09-08 | — | — | US | disclosed |