Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249698 | 0.80 | CYP1A2 (0.38) | GLSMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11244852 | 0.72 | POLB (0.34) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL11263022 | 0.72 | POLB (0.34) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL5179498 | 0.70 | ALDH1A1 (0.40) | MAPTKMT2AALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL9125705 | 0.69 | KMT2A (0.40) | MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11247894 | 0.68 | TSHR (0.42) | MEN1KMT2AALDH1A1 | |
| SCHEMBL11241971 | 0.68 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL11247965 | 0.68 | NPC1 (0.38) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL9274763 | 0.66 | PDK1 (0.39) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL11373826 | 0.65 | NLRP3 (0.41) | MAPTMEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318915-A | Substituted guandines and methods of preparation thereof | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1982-03-09 | — | — | US | disclosed |