Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249009 | 0.82 | CYP1A2 (0.39) | CYP1A2KDM4EALDH1A1LMNAF2 | |
| SCHEMBL11247962 | 0.80 | GLS (0.40) | ALDH1A1LMNAF2F10PLAU | |
| Hydrochloric Acid SCHEMBL11256885 | 0.76 | ALDH1A1 (0.36) | CYP1A2KDM4EALDH1A1LMNACXCL8 | |
| SCHEMBL11244852 | 0.73 | POLB (0.34) | ALDH1A1KMT2AMEN1MAPK1POLB | |
| SCHEMBL11263022 | 0.73 | POLB (0.34) | ALDH1A1KMT2AMEN1MAPK1POLB | |
| SCHEMBL11247894 | 0.71 | TSHR (0.42) | ALDH1A1CXCL8KMT2AMEN1SLC1A3 | |
| SCHEMBL11241971 | 0.71 | ALDH1A1 (0.41) | CYP1A2ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL8668403 | 0.70 | MAPT (0.47) | KDM4EALDH1A1F2F10PLAU | |
| SCHEMBL11249700 | 0.70 | HTR2B (0.47) | CYP1A2KDM4ELMNAADRA2AKMT2A | |
| SCHEMBL5179498 | 0.70 | ALDH1A1 (0.40) | CYP1A2ALDH1A1LMNAKMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318915-A | Substituted guandines and methods of preparation thereof | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1982-03-09 | — | — | US | disclosed |