Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | IDH2 | P48735 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11158949 | 0.82 | MAPT (0.44) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL11257741 | 0.77 | LMNA (0.48) | NPC1RAB9AIDH2SMN1; SMN2MAPT | |
| SCHEMBL11254098 | 0.75 | NPC1 (0.49) | NPC1RAB9AIDH2SMN1; SMN2MAPT | |
| SCHEMBL11267290 | 0.72 | NPC1 (0.46) | NPC1RAB9AIDH2SMN1; SMN2MAPT | |
| SCHEMBL11029494 | 0.71 | PKM (0.34) | LMNANPSR1CYP2C9CYP2C19 | |
| SCHEMBL11254673 | 0.71 | NPSR1 (0.46) | NPC1RAB9AIDH2SMN1; SMN2MAPT | |
| SCHEMBL11261449 | 0.68 | NPC1 (0.42) | NPC1RAB9AIDH2SMN1; SMN2MAPT | |
| SCHEMBL10619199 | 0.67 | SMN1; SMN2 (0.74) | NPC1RAB9AIDH2SMN1; SMN2MAPT | |
| SCHEMBL10539161 | 0.67 | LMNA (0.54) | NPC1RAB9AIDH2SMN1; SMN2MAPT | |
| SCHEMBL11246375 | 0.65 | KCNH3 (0.61) | SMN1; SMN2MAPTLMNAGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339577-A | CROSSLINKING INHIBITORS FOR RUBBERS | MONSANTO COMPANY (US) | 1982-07-13 | — | — | US | disclosed |
| US-4301260-A | Vulcanizable rubber compositions scorch inhibited by 2-(thioamino)-4,6-diamino-1,3,5-triazines | MONSANTO COMPANY (US) | 1981-11-17 | — | — | US | disclosed |