Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | IDH2 | P48735 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252354 | 0.79 | APP (0.47) | NPSR1LMNANPC1RAB9ACYP1A2 | |
| SCHEMBL11155028 | 0.78 | MAPT (0.47) | LMNANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL11265077 | 0.77 | KCNH3 (0.57) | NPSR1LMNAMAPTMEN1KMT2A | |
| SCHEMBL11254098 | 0.75 | NPC1 (0.49) | NPSR1LMNANPC1RAB9AIDH2 | |
| SCHEMBL11256328 | 0.74 | ALDH1A1 (0.51) | NPSR1LMNASMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL11249081 | 0.73 | LMNA (0.48) | NPSR1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11267290 | 0.72 | NPC1 (0.46) | NPSR1LMNANPC1RAB9AIDH2 | |
| SCHEMBL6897708 | 0.71 | CYP2D6 (0.47) | LMNANPC1RAB9AMAPTCYP1A2 | |
| SCHEMBL11248933 | 0.71 | NPC1 (0.45) | NPSR1LMNANPC1RAB9AIDH2 | |
| SCHEMBL11263145 | 0.70 | CTSS (0.51) | LMNANPC1RAB9ASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339577-A | CROSSLINKING INHIBITORS FOR RUBBERS | MONSANTO COMPANY (US) | 1982-07-13 | — | — | US | disclosed |
| US-4301260-A | Vulcanizable rubber compositions scorch inhibited by 2-(thioamino)-4,6-diamino-1,3,5-triazines | MONSANTO COMPANY (US) | 1981-11-17 | — | — | US | disclosed |