Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253776 | 0.88 | ROS1 (0.41) | KDM4EPTGDR2MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL11255704 | 0.85 | PTGDR2 (0.49) | IDO1TDO2KDM4ECSNK2A2CSNK2B | |
| SCHEMBL11248945 | 0.84 | IDO1 (0.42) | KDRIDO1TDO2KDM4ECSNK2A2 | |
| SCHEMBL11500393 | 0.80 | PTGDR2 (0.45) | IDO1TDO2KDM4ECSNK2A2CSNK2B | |
| SCHEMBL11251095 | 0.78 | ALDH1A1 (0.47) | KDM4EMAPTSMN1; SMN2POLBKMT2A | |
| SCHEMBL11262405 | 0.77 | TDO2 (0.48) | IDO1TDO2KDM4ECSNK2A2CSNK2B | |
| SCHEMBL11252609 | 0.77 | PKM (0.39) | KDM4ERXFP1MAPTMAPK1POLB | |
| SCHEMBL11253962 | 0.77 | TDO2 (0.45) | IDO1TDO2KDM4ECSNK2A2CSNK2B | |
| SCHEMBL11258880 | 0.77 | MMP2 (0.51) | KDM4EPTGDR2TDP1ALDH1A1PDE3B | |
| SCHEMBL11253180 | 0.77 | GAA (0.49) | KDM4EMAPTMAPK1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |