Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11500393 | 0.94 | PTGDR2 (0.45) | PTGDR2KDM4EDRD2TDP1CSNK2A2 | |
| SCHEMBL11251835 | 0.89 | TDP1 (0.54) | PTGDR2KDM4ETDP1CYP1A2ALDH1A1 | |
| SCHEMBL11248945 | 0.88 | IDO1 (0.42) | PTGDR2KDM4EDRD2CSNK2A2CSNK2B | |
| SCHEMBL11246786 | 0.86 | LMNA (0.48) | PTGDR2KDM4ETDP1CYP1A2ALDH1A1 | |
| SCHEMBL11261678 | 0.86 | TDP1 (0.45) | PTGDR2KDM4ETDP1CYP1A2ALDH1A1 | |
| SCHEMBL11262804 | 0.86 | TDP1 (0.45) | PTGDR2KDM4ETDP1CYP1A2MEN1 | |
| SCHEMBL11266566 | 0.85 | KDR (0.40) | PTGDR2KDM4ETDP1CSNK2A2CSNK2B | |
| SCHEMBL11250186 | 0.83 | PTGDR2 (0.43) | PTGDR2KDM4ETDP1CYP1A2ALDH1A1 | |
| SCHEMBL11259158 | 0.83 | TDP1 (0.42) | PTGDR2KDM4ETDP1CYP1A2POLB | |
| SCHEMBL11258880 | 0.83 | MMP2 (0.51) | PTGDR2KDM4ETDP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | claimed |
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |