Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 5/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.48 |
| ▸ | HTR1A | P08908 | 4/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | HTR2B | P41595 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | NR2E1 | Q9Y466 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253705 | 0.88 | AMY1A (0.58) | ADRB2HTR1ADRD3ADRA2ASLC6A2 | |
| SCHEMBL11248636 | 0.83 | ADRB2 (0.57) | ADRB2SLC6A2PTGS1CYP2D6ADRB1 | |
| SCHEMBL11256396 | 0.77 | ADRB2 (0.51) | ADRB2HTR1ADRD3ADRA2ASLC6A2 | |
| SCHEMBL11851746 | 0.73 | ADRB2 (0.71) | ADRB2HTR1ADRD3ADRA2ASLC6A2 | |
| SCHEMBL11258657 | 0.70 | ATP4A (0.51) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL11244652 | 0.70 | CYP2D6 (0.58) | CYP2D6LMNAALDH1A1NFKB1SMN1; SMN2 | |
| SCHEMBL28671884 | 0.69 | CYP2D6 (0.70) | ADRB2HTR1ADRD3ADRA2ASLC6A2 | |
| SCHEMBL28671887 | 0.69 | CYP2D6 (0.70) | ADRB2HTR1ADRD3ADRA2ASLC6A2 | |
| SCHEMBL11868102 | 0.69 | ADRB2 (0.82) | ADRB2HTR1ADRD3ADRA2ASLC6A2 | |
| SCHEMBL22488596 | 0.69 | AMY1A (0.53) | HPSELMNAALDH1A1TP53NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338330-A | HYPOTENSIVE AGENTS | CONTINENTAL PHARMA (BE) | 1982-07-06 | — | — | US | disclosed |