Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248636 | 0.84 | ADRB2 (0.57) | ADRB2ADRB1ADRB3CYP2D6PTGS1 | |
| SCHEMBL11249989 | 0.77 | HPSE (0.51) | ADRB2ADRB1ADRB3CYP2D6PTGS1 | |
| SCHEMBL11253705 | 0.77 | AMY1A (0.58) | ADRB2ADRB1ADRB3CYP2D6PTGS1 | |
| SCHEMBL13060614 | 0.71 | ACHE (0.46) | ABCB11 | |
| SCHEMBL11258657 | 0.71 | ATP4A (0.51) | — | |
| SCHEMBL11244652 | 0.70 | CYP2D6 (0.58) | CYP2D6 | |
| SCHEMBL28201503 | 0.70 | NPC1 (0.41) | — | |
| SCHEMBL3169760 | 0.70 | DGAT1 (0.56) | — | |
| SCHEMBL3169776 | 0.70 | DGAT1 (0.56) | — | |
| SCHEMBL7809148 | 0.70 | ADRB2 (0.64) | ADRB2ADRB1ADRB3CYP2D6PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338330-A | HYPOTENSIVE AGENTS | CONTINENTAL PHARMA (BE) | 1982-07-06 | — | — | US | disclosed |