Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810870 | 1.00 | MEN1 (0.52) | MEN1KMT2AALDH1A1GAAPKM | |
| SCHEMBL11250417 | 0.85 | PKM (0.56) | MEN1KMT2AALDH1A1PKMMAPK1 | |
| SCHEMBL9810865 | 0.74 | ALOX5 (0.50) | MEN1KMT2AALDH1A1HSP90AA1ALOX5 | |
| SCHEMBL9810862 | 0.74 | ALOX5 (0.50) | MEN1KMT2AALDH1A1HSP90AA1ALOX5 | |
| SCHEMBL9810873 | 0.73 | ALOX5 (0.49) | MEN1KMT2AALDH1A1GAAHSP90AA1 | |
| SCHEMBL9810874 | 0.73 | ALOX5 (0.49) | MEN1KMT2AALDH1A1GAAHSP90AA1 | |
| SCHEMBL9810847 | 0.71 | ALOX5 (0.50) | MEN1KMT2AALDH1A1HSP90AA1ALOX5 | |
| SCHEMBL11155936 | 0.70 | ATM (0.54) | MEN1KMT2AALDH1A1TSHRHSP90AA1 | |
| SCHEMBL11399593 | 0.70 | SIGMAR1 (0.51) | MEN1KMT2AALDH1A1GAAPKM | |
| SCHEMBL11489613 | 0.70 | SIGMAR1 (0.51) | MEN1KMT2AALDH1A1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262870-B1 | MORPHOLINE, PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-06-12 | — | — | EP | disclosed |
| US-4837236-A | CONTROLLING PHYTOPATHOGENS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-06-06 | — | — | US | disclosed |
| EP-0262870-A2 | Morpholine, piperidine and tetrahydropyridine derivatives, processes for their preparation and their use as fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-04-06 | — | — | EP | disclosed |