Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.32 |
| ▸ | F13A1 | P00488 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11182853 | 0.90 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1APOBEC3AAPOBEC3GHDAC6 | |
| SCHEMBL7027997 | 0.72 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1APOBEC3AAPOBEC3GHDAC6 | |
| Hydrochloric Acid SCHEMBL7021156 | 0.71 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1APOBEC3AAPOBEC3GHDAC6 | |
| SCHEMBL11267315 | 0.68 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1APOBEC3AAPOBEC3GHDAC6 | |
| SCHEMBL11529642 | 0.64 | HDAC3 (0.36) | SMN1; SMN2ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL11528657 | 0.62 | HDAC3 (0.35) | SMN1; SMN2ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL828869 | 0.60 | KDM4E (0.42) | SMN1; SMN2ALDH1A1MAPK1LMNAGABRP | |
| SCHEMBL69789 | 0.55 | SMN1; SMN2 (0.78) | SMN1; SMN2ALDH1A1HDAC3HDAC4HDAC1 | |
| Glutarate SCHEMBL3911885 | 0.54 | SLC22A6 (0.85) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| Adipic Acid SCHEMBL1361644 | 0.54 | LMNA (0.85) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358590-A | 6-Carboxy- and 6-(ω-carboxyalkyl)-3-mercapto-4-amino-1,2,4-triazin-5(4H)-ones | WILEY RICHARD H | 1982-11-09 | — | — | US | claimed |
| US-4358590-A | 6-Carboxy- and 6-(ω-carboxyalkyl)-3-mercapto-4-amino-1,2,4-triazin-5(4H)-ones | WILEY RICHARD H | 1982-11-09 | — | — | US | disclosed |