Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7021156 | 0.98 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2APOBEC3AAPOBEC3GHDAC6 | |
| SCHEMBL11182853 | 0.81 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2APOBEC3AAPOBEC3GHDAC6 | |
| SCHEMBL7031322 | 0.79 | LMNA (0.46) | ALDH1A1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL11267315 | 0.78 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2APOBEC3AAPOBEC3GHDAC6 | |
| Hydrochloric Acid SCHEMBL7030321 | 0.77 | LMNA (0.45) | ALDH1A1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL11250463 | 0.72 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2APOBEC3AAPOBEC3GHDAC6 | |
| SCHEMBL7028443 | 0.72 | KDM4E (0.33) | ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL8517214 | 0.70 | TBXAS1 (0.41) | ALDH1A1 | |
| SCHEMBL17272788 | 0.69 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2HDAC6KDM4ETP53 | |
| SCHEMBL9802011 | 0.68 | NPSR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889884-B1 | 1,2,4-TRIAZINE DERIVATIVES FOR THE INHIBITION OF PROTEIN GLYCOSYLATION | ALTEON INC (US) | 2003-01-29 | — | — | EP | disclosed |
| US-6380192-B1 | FOR INHIBITING NONENZYMATIC CROSS-LINKING (PROTEIN AGING) | ALTEON, INC. | 2002-04-30 | — | — | US | disclosed |
| US-6060470-A | Triazine compounds and methods of use therefor | ALTEON, INC. | 2000-05-09 | — | — | US | disclosed |
| US-5932578-A | CAPABLE OF INHIBITING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS OF TARGET PROTEINS. FOOD SPOILAGE AND ANIMAL PROTEIN AGING CAN BE TREATED. | ALTEON INC. (US) | 1999-08-03 | — | — | US | disclosed |