Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270017 | 0.91 | QPCT (0.42) | LMNAQPCTKDM4EPRKCICYP19A1 | |
| SCHEMBL11256462 | 0.89 | LMNA (0.38) | LMNAQPCTRAB9ANPC1GFER | |
| SCHEMBL11254266 | 0.85 | LMNA (0.40) | LMNAQPCTRAB9ANPC1GFER | |
| SCHEMBL11262886 | 0.84 | CYP19A1 (0.41) | LMNAQPCTPOLBPRKCICYP19A1 | |
| SCHEMBL10785619 | 0.83 | TBXAS1 (0.43) | LMNAQPCTKDM4EPRKCI | |
| SCHEMBL11266390 | 0.83 | HMOX1 (0.42) | CYP19A1HMOX1 | |
| SCHEMBL11270666 | 0.83 | CYP2A6 (0.38) | QPCTCYP19A1HMOX1 | |
| SCHEMBL11262771 | 0.82 | CYP1A2 (0.39) | QPCTPOLBCYP19A1HMOX1 | |
| SCHEMBL10780799 | 0.82 | TBXAS1 (0.40) | QPCTPRKCI | |
| SCHEMBL11264763 | 0.81 | TSHR (0.39) | LMNAKDM4EPRKCICYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |