Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 10/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
| ▸ | FBP1 | P09467 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099439 | 0.87 | FFAR2 (0.58) | FFAR2S1PR3KCNH2MEN1GAA | |
| SCHEMBL11254785 | 0.86 | ELANE (0.40) | S1PR3GAAKMT2AS1PR1MAPT | |
| SCHEMBL11269418 | 0.86 | ALDH1A1 (0.46) | S1PR3GAAS1PR4RAB9A | |
| SCHEMBL11102900 | 0.82 | HDAC8 (0.45) | FFAR2S1PR3KCNH2MEN1GAA | |
| SCHEMBL11098158 | 0.78 | SMN1; SMN2 (0.45) | FFAR2GAAKMT2AMAPTRAB9A | |
| SCHEMBL11100838 | 0.76 | RAB9A (0.51) | S1PR3GAAKMT2AS1PR1FBP1 | |
| SCHEMBL11099522 | 0.73 | NPC1 (0.54) | GAAMAPTRAB9A | |
| SCHEMBL16972933 | 0.73 | NPC1 (0.54) | GAAMAPTRAB9A | |
| SCHEMBL16972931 | 0.73 | NPC1 (0.54) | GAAMAPTRAB9A | |
| SCHEMBL11100985 | 0.73 | KMO (0.42) | MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318905-A | Nonapeptide and decapeptide agonists of luteinizing hormone releasing hormone containing heterocyclic amino acid residues | SYNTEX (U.S.A.) INC. (US) | 1982-03-09 | — | — | US | disclosed |
| EP-0042753-A1 | Nonapeptide and decapeptide agonists of luteinizing hormone releasing hormone containing heterocyclic amino acid residues, methods for their preparation, pharmaceutical compounds containing them, and their pharmaceutical use | SYNTEX (U.S.A.) INC. (US) | 1981-12-30 | — | — | EP | disclosed |