Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | GUSB | P08236 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11264419 | 0.82 | PDE5A (0.43) | METAP2METAP1 | |
| SCHEMBL11255428 | 0.81 | ALDH1A1 (0.44) | METAP2METAP1NR3C1PGRNR3C2 | |
| SCHEMBL11261992 | 0.80 | METAP2 (0.33) | METAP2METAP1 | |
| SCHEMBL11262531 | 0.78 | AMY1A (0.41) | NPY5R | |
| SCHEMBL11253114 | 0.78 | AMY1A (0.47) | — | |
| SCHEMBL11259880 | 0.78 | AMY1A (0.51) | METAP2METAP1GUSB | |
| SCHEMBL11262388 | 0.78 | AMY1A (0.37) | — | |
| SCHEMBL11266547 | 0.77 | RHEB (0.31) | — | |
| SCHEMBL11264095 | 0.71 | AMY1A (0.34) | — | |
| SCHEMBL11251284 | 0.67 | HTR2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329459-A | ENDOPEROXIDE CYCLOXGENASE INHIBITORS | THE UPJOHN COMPANY (US) | 1982-05-11 | — | — | US | claimed |
| US-4329459-A | ENDOPEROXIDE CYCLOXGENASE INHIBITORS | THE UPJOHN COMPANY (US) | 1982-05-11 | — | — | US | disclosed |