Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.51 |
| ▸ | MMP12 | P39900 | 3/20 | 0.51 |
| ▸ | MMP9 | P14780 | 2/20 | 0.51 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | MMP14 | P50281 | 2/20 | 0.47 |
| ▸ | MMP16 | P51512 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246786 | 0.86 | LMNA (0.48) | PTGDR2TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL11251835 | 0.85 | TDP1 (0.54) | MMP2MMP12MMP9MMP8MMP13 | |
| SCHEMBL11261678 | 0.83 | TDP1 (0.45) | PTGDR2PTGS2PTGS1TDP1KDM4E | |
| SCHEMBL11262804 | 0.83 | TDP1 (0.45) | MMP2MMP12MMP9MMP13MMP14 | |
| SCHEMBL11255704 | 0.83 | PTGDR2 (0.49) | PTGDR2PDE3ATDP1KDM4EALDH1A1 | |
| SCHEMBL11259158 | 0.82 | TDP1 (0.42) | PTGDR2TDP1KDM4E | |
| SCHEMBL11250186 | 0.82 | PTGDR2 (0.43) | PTGDR2TDP1KDM4EALDH1A1 | |
| SCHEMBL11246793 | 0.80 | PPARD (0.47) | PPARDPTGDR2TDP1 | |
| SCHEMBL11499255 | 0.80 | GAA (0.46) | PTGDR2TDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL11259907 | 0.79 | IDO1 (0.49) | PTGDR2PTGS2PTGS1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |