Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251835 | 0.89 | TDP1 (0.54) | TDP1MMP1MMP2MMP3MMP9 | |
| SCHEMBL11255704 | 0.86 | PTGDR2 (0.49) | TDP1PTGDR2MEN1POLBKMT2A | |
| SCHEMBL11246786 | 0.86 | LMNA (0.48) | TDP1PTGDR2MEN1POLBKMT2A | |
| SCHEMBL11261678 | 0.86 | TDP1 (0.45) | TDP1PTGDR2MEN1POLBKMT2A | |
| SCHEMBL11246793 | 0.86 | PPARD (0.47) | TDP1PTGDR2 | |
| SCHEMBL11259158 | 0.83 | TDP1 (0.42) | TDP1PTGDR2POLBKDM4ECYP1A2 | |
| SCHEMBL11250186 | 0.83 | PTGDR2 (0.43) | TDP1PTGDR2POLBKDM4ECYP1A2 | |
| SCHEMBL11258880 | 0.83 | MMP2 (0.51) | TDP1MMP1MMP2MMP3MMP9 | |
| SCHEMBL11259907 | 0.82 | IDO1 (0.49) | TDP1PTGDR2MEN1POLBKMT2A | |
| SCHEMBL11500393 | 0.81 | PTGDR2 (0.45) | TDP1PTGDR2MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56092273-A | — | — | None | — | — | JP | disclosed |
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| JP-S5692273-A | 1-PHENYLISOQUINOLINE DERIVATIVE | TEIKOKU HORMONE MFG CO LTD | 1981-07-25 | — | — | JP | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |