Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 9/20 | 0.46 |
| ▸ | RAB9A | P51151 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.45 |
| ▸ | RELA | Q04206 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11255465 | 0.84 | RAB9A (0.61) | HSD11B1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Clofentezine SCHEMBL74002 | 0.82 | LDHA (0.59) | HSD11B1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Clofentezine SCHEMBL5022593 | 0.82 | LDHA (0.59) | HSD11B1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Clofentezine SCHEMBL29375770 | 0.82 | LDHA (0.59) | HSD11B1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Clofentezine SCHEMBL30917908 | 0.82 | LDHA (0.59) | HSD11B1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1045000 | 0.80 | CYP2A6 (0.65) | HSD11B1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Clofentezine SCHEMBL28407354 | 0.80 | LDHA (0.57) | HSD11B1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Clofentezine SCHEMBL27980858 | 0.80 | LDHA (0.57) | HSD11B1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Clofentezine SCHEMBL27876726 | 0.80 | LDHA (0.57) | HSD11B1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22357676 | 0.79 | HSD11B1 (0.52) | HSD11B1ALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005912-B1 | ACARICIDAL, LARVICIDAL AND OVICIDAL TETRAZINE DERIVATIVES AND COMPOSITIONS, PROCESSES FOR THEIR PREPARATION AND METHODS OF USING THEM | FBC LIMITED (GB) | 1982-07-14 | — | — | EP | claimed |
| US-4237127-A | MITICIDES, LARVICIDES, OVICIDES | FISONS LIMITED (GB) | 1980-12-02 | — | — | US | claimed |
| EP-0005912-A1 | Acaricidal, larvicidal and ovicidal tetrazine derivatives and compositions, processes for their preparation and methods of using them | FBC LIMITED (GB) | 1979-12-12 | — | — | EP | claimed |
| EP-0005912-B1 | ACARICIDAL, LARVICIDAL AND OVICIDAL TETRAZINE DERIVATIVES AND COMPOSITIONS, PROCESSES FOR THEIR PREPARATION AND METHODS OF USING THEM | FBC LIMITED (GB) | 1982-07-14 | — | — | EP | disclosed |
| US-4237127-A | MITICIDES, LARVICIDES, OVICIDES | FISONS LIMITED (GB) | 1980-12-02 | — | — | US | disclosed |
| EP-0005912-A1 | Acaricidal, larvicidal and ovicidal tetrazine derivatives and compositions, processes for their preparation and methods of using them | FBC LIMITED (GB) | 1979-12-12 | — | — | EP | disclosed |