Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263009 | 0.85 | PIK3CA (0.35) | ALDH1A1SMN1; SMN2TDO2KDM4EHPGD | |
| SCHEMBL11260467 | 0.85 | TDO2 (0.42) | MAPTALDH1A1LMNATDO2MEN1 | |
| SCHEMBL11260164 | 0.82 | TDO2 (0.33) | MAPTALDH1A1TDO2AURKA | |
| SCHEMBL11257643 | 0.79 | PSEN1 (0.39) | MAPTALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL11254978 | 0.76 | SYK (0.35) | SYKMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11262913 | 0.74 | ALDH1A1 (0.39) | SYKMAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL11497570 | 0.70 | ALDH1A1 (0.40) | MAPTALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL2163003 | 0.69 | S100A4 (0.56) | SYKMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11255165 | 0.69 | CNR2 (0.38) | SYKMAPTALDH1A1ADKCNR2 | |
| SCHEMBL11254442 | 0.68 | KDM4E (0.38) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |