Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 4/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PTPRB | P23467 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261330 | 0.83 | TACR1 (0.32) | TACR1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11261894 | 0.81 | PGR (0.38) | RORCHSD17B10 | |
| SCHEMBL11261899 | 0.78 | TACR1 (0.32) | TACR1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL3899407 | 0.74 | LMNA (0.50) | HPGD | |
| SCHEMBL11307507 | 0.71 | CD69 (0.43) | — | |
| SCHEMBL2264742 | 0.69 | POLB (0.45) | RORC | |
| SCHEMBL1847365 | 0.68 | AGBL2 (0.31) | — | |
| SCHEMBL11273478 | 0.68 | DRD2 (0.46) | — | |
| SCHEMBL11266609 | 0.67 | MLYCD (0.40) | HPGDPTPRBHSD17B10 | |
| SCHEMBL11261924 | 0.66 | POLB (0.50) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322434-A | N-Substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| US-4267193-A | N-substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1981-05-12 | — | — | US | disclosed |