Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257657 | 0.84 | LMNA (0.46) | GABRA1GABRB2PSMD14COPS5LMNA | |
| SCHEMBL11250074 | 0.83 | LOXL2 (0.49) | GABRA1GABRB2PSMD14COPS5LMNA | |
| SCHEMBL7358290 | 0.80 | DPP4 (0.33) | KDM4EMAPTTSHRMEN1KMT2A | |
| SCHEMBL11258743 | 0.79 | ALDH1A1 (0.32) | GABRA1GABRB2 | |
| SCHEMBL11261355 | 0.78 | TDP1 (0.50) | KDM4EMAPT | |
| SCHEMBL20009335 | 0.77 | CYP1A2 (0.50) | PSMD14COPS5LMNAKDM4EMAPT | |
| SCHEMBL11267468 | 0.74 | ANPEP (0.38) | MAPTMEN1KMT2A | |
| SCHEMBL28538582 | 0.74 | LMNA (0.41) | GABRA1GABRB2LMNATSHR | |
| SCHEMBL13051656 | 0.74 | GABRA1 (0.40) | GABRA1GABRB2PSMD14COPS5LMNA | |
| SCHEMBL11255746 | 0.74 | ALDH1A1 (0.40) | LMNAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |