Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | IDH1 | O75874 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11255956 | 0.91 | MEN1 (0.42) | TAS2R14MEN1KMT2AIDH1MAPT | |
| SCHEMBL11049781 | 0.87 | KIF11 (0.46) | MEN1KMT2AHTTBRAFPDE2A | |
| SCHEMBL11248814 | 0.85 | MAPT (0.47) | MEN1KMT2AIDH1MAPTHTT | |
| SCHEMBL11050004 | 0.84 | CA12 (0.47) | MEN1KMT2AIDH1MAPTHTT | |
| SCHEMBL11250280 | 0.84 | LMNA (0.41) | MEN1KMT2AMAPTHTTCYP1A2 | |
| SCHEMBL11053855 | 0.84 | MAPT (0.40) | TAS2R14MEN1KMT2AMAPTHTT | |
| SCHEMBL11250969 | 0.83 | TAS2R14 (0.47) | TAS2R14MEN1KMT2AMAPTHTT | |
| SCHEMBL11263600 | 0.82 | GAA (0.48) | MEN1KMT2AMAPTHTTGAA | |
| SCHEMBL11258056 | 0.82 | MEN1 (0.47) | MEN1KMT2AIDH1MAPTHTT | |
| SCHEMBL11049998 | 0.81 | MAPT (0.39) | MEN1KMT2AMAPTHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |