Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049781 | 0.88 | KIF11 (0.46) | LMNAL3MBTL1ANO1MEN1KMT2A | |
| SCHEMBL11255956 | 0.87 | MEN1 (0.42) | LMNAL3MBTL1ANO1MEN1KMT2A | |
| SCHEMBL11250897 | 0.86 | PKM (0.48) | ANO1MEN1KMT2AHTTPKM | |
| SCHEMBL11053855 | 0.85 | MAPT (0.40) | LMNAL3MBTL1ANO1MEN1KMT2A | |
| SCHEMBL11050004 | 0.85 | CA12 (0.47) | LMNAMEN1KMT2ACYP1A2HTT | |
| SCHEMBL11261823 | 0.84 | TAS2R14 (0.44) | MEN1KMT2ACYP1A2HTTPDE2A | |
| SCHEMBL11255374 | 0.83 | KIF11 (0.43) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11056245 | 0.82 | NPC1 (0.46) | LMNAANO1MEN1KMT2AHTT | |
| SCHEMBL11056677 | 0.82 | HTT (0.46) | ANO1MEN1KMT2AHTT | |
| SCHEMBL11052503 | 0.82 | KCNMA1 (0.53) | MEN1KMT2AHTTPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |
| US-4220658-A | Treatment of hypertension with amidinoureas | WILLIAM H. RORER, INC. (US) | 1980-09-02 | — | — | US | disclosed |
| US-4088785-A | HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1978-05-09 | — | — | US | disclosed |