Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | CASP7 | P55210 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terbutaline SCHEMBL4391 | 0.81 | LMNA (1.00) | LMNAADRB2HIF1ATSHRCASP7 | |
| Terbutaline SCHEMBL41869 | 0.81 | LMNA (1.00) | LMNAADRB2HIF1ATSHRCASP7 | |
| Terbutaline SCHEMBL13327959 | 0.81 | LMNA (1.00) | LMNAADRB2HIF1ATSHRCASP7 | |
| Terbutaline SCHEMBL11703058 | 0.79 | ADRB2 (0.96) | LMNAADRB2HIF1ATSHRCASP7 | |
| Terbutaline SCHEMBL404480 | 0.79 | ADRB2 (0.96) | LMNAADRB2HIF1ATSHRCASP7 | |
| Terbutaline SCHEMBL16553265 | 0.79 | LMNA (0.81) | LMNAADRB2HIF1ATSHRCASP7 | |
| SCHEMBL11269803 | 0.78 | ADRB2 (0.49) | LMNAADRB2HIF1ATSHRCASP7 | |
| Terbutaline SCHEMBL28876660 | 0.77 | LMNA (0.79) | LMNAADRB2HIF1ATSHRCASP7 | |
| Terbutaline SCHEMBL27361880 | 0.77 | ADRB2 (0.79) | LMNAADRB2HIF1ATSHRCASP7 | |
| Terbutaline SCHEMBL26462 | 0.77 | LMNA (1.00) | LMNAADRB2HIF1ATSHRCASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337272-A | BRONCHODILATOR AGENTS | VALEAS S. R. L. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1982-06-29 | — | — | US | disclosed |
| US-4252824-A | BRONCHODILATOR AGENTS | VALEAS S.R.L., INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1981-02-24 | — | — | US | disclosed |