Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270936 | 0.88 | RXRA (0.33) | HSD11B1MEN1KMT2ARXRARXRB | |
| SCHEMBL11264342 | 0.86 | MLYCD (0.35) | — | |
| SCHEMBL11261899 | 0.83 | TACR1 (0.32) | TACR1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11261308 | 0.83 | L3MBTL1 (0.41) | RXRARXRBPPARGRXRGALDH1A1 | |
| SCHEMBL11262905 | 0.80 | MEN1 (0.33) | TACR1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL11625445 | 0.75 | SOAT1 (0.35) | — | |
| SCHEMBL11270933 | 0.74 | MLYCD (0.39) | — | |
| SCHEMBL11346217 | 0.72 | CA1 (0.47) | — | |
| SCHEMBL11266630 | 0.71 | ALDH1A1 (0.38) | RXRARXRBRXRGALDH1A1 | |
| SCHEMBL11275932 | 0.69 | PGK1 (0.33) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322434-A | N-Substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| US-4267193-A | N-substituted-4-(polyfluoro-2-hydroxy-2-propyl)anilines and compounds related thereto | SCHERING CORPORATION (US) | 1981-05-12 | — | — | US | disclosed |