Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11833872 | 0.84 | HRH3 (0.40) | HRH3HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL11266030 | 0.83 | FPR2 (0.30) | — | |
| SCHEMBL11275928 | 0.82 | HRH3 (0.40) | HRH3HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL11277201 | 0.81 | ADORA3 (0.47) | HRH3HTR3APDE10AHRH4 | |
| SCHEMBL11668842 | 0.72 | HRH3 (0.37) | HRH3HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL10472440 | 0.69 | RAB9A (0.58) | HRH3HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL11488417 | 0.69 | PDE10A (0.42) | HRH3HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL11836835 | 0.67 | TSHR (0.48) | HRH3HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL11267038 | 0.66 | NPC1 (0.43) | MEN1KMT2A | |
| SCHEMBL11263670 | 0.66 | MAPT (0.42) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327095-A | TRANQUICIZERS, ANTICONVULSANTS DECONTRACTURANTS AND HYPNOGENIC AGENTS | RHONE-POULENC INDUSTRIES (FR) | 1982-04-27 | — | — | US | disclosed |