Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126921 | 0.89 | MAPT (0.37) | MAPTPOLBF10LMNATP53 | |
| SCHEMBL1989043 | 0.89 | MAPT (0.38) | MAPTPOLBF10TP53ATM | |
| SCHEMBL1999344 | 0.88 | MAPT (0.41) | MAPTPOLBP2RY1RAB9A | |
| SCHEMBL1127171 | 0.87 | POLB (0.42) | MAPTPOLBLMNACYP3A4 | |
| SCHEMBL1126883 | 0.86 | SIGMAR1 (0.38) | MAPTPOLBF10RAB9A | |
| SCHEMBL1126928 | 0.86 | MAPT (0.39) | MAPTPOLBF10LMNATP53 | |
| SCHEMBL1126811 | 0.84 | MAPT (0.36) | MAPTPOLBF10LMNATP53 | |
| SCHEMBL1994130 | 0.80 | MAPT (0.39) | MAPTPOLBLMNATP53 | |
| SCHEMBL1127002 | 0.78 | AR (0.40) | MAPTP2RY1LMNAATMRAB9A | |
| SCHEMBL1126909 | 0.77 | MEN1 (0.41) | MAPTPOLBLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |