Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126696 | 0.84 | MAPT (0.50) | MEN1KMT2AMAPTGAANPC1 | |
| SCHEMBL1126487 | 0.83 | MAPT (0.51) | MEN1KMT2AMAPTGAANPC1 | |
| SCHEMBL1127109 | 0.83 | MAPT (0.52) | MEN1KMT2AMAPTGAANPC1 | |
| SCHEMBL19661313 | 0.82 | GAA (0.42) | MEN1KMT2AMAPTGAANPC1 | |
| SCHEMBL30235329 | 0.82 | ALDH1A1 (0.48) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL1992485 | 0.82 | ALDH1A1 (0.48) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL1992803 | 0.81 | REV1 (0.44) | MEN1KMT2AMAPTGAANPC1 | |
| SCHEMBL1127203 | 0.81 | NPY2R (0.44) | MEN1KMT2AMAPTGAANPC1 | |
| SCHEMBL1127152 | 0.81 | NAMPT (0.53) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL1993111 | 0.81 | ALDH1A1 (0.42) | MEN1KMT2AMAPTGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | claimed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | claimed |