SCHEMBL1126883

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126921	0.89	MAPT (0.37)	SIGMAR1TMEM97MAPTPOLBHTR2C
	SCHEMBL1126928	0.89	MAPT (0.39)	MAPTPOLBHTR2CDRD3F10
	SCHEMBL1989043	0.89	MAPT (0.38)	MAPTPOLBF10
	SCHEMBL1126560	0.89	SIGMAR1 (0.40)	SIGMAR1TMEM97HRH1HRH3ADRB1
	SCHEMBL1999344	0.88	MAPT (0.41)	MAPTPOLBRAB9A
	SCHEMBL1126522	0.86	MAPT (0.37)	MAPTPOLBF10RAB9A
	SCHEMBL1127171	0.86	POLB (0.42)	MAPTPOLBDRD3DRD2DRD4
	SCHEMBL1126811	0.84	MAPT (0.36)	MAPTPOLBF10
	SCHEMBL1994130	0.83	MAPT (0.39)	MAPTPOLBHTR2CHTR2ASLC6A4
	SCHEMBL1127002	0.78	AR (0.40)	MAPTHTR2CDRD3RAB9AHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.