SCHEMBL1126692

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1018875	0.83	SIRT6 (0.54)	SIRT6POLBMAPTLMNAMEN1
	SCHEMBL942805	0.82	SIRT6 (0.56)	SIRT6POLBMAPTLMNAMEN1
	SCHEMBL22495369	0.80	SIRT6 (0.50)	SIRT6POLBMAPTLMNAMEN1
	SCHEMBL2233842	0.80	MEN1 (0.59)	SIRT6POLBMAPTLMNAMEN1
	SCHEMBL943495	0.79	LMNA (0.58)	SIRT6POLBMAPTLMNAMEN1
	SCHEMBL15271381	0.78	SIRT6 (0.81)	SIRT6POLBMAPTLMNAMEN1
	SCHEMBL6151230	0.78	SIRT6 (0.81)	SIRT6POLBMAPTLMNAMEN1
	SCHEMBL942358	0.78	MAPT (0.54)	SIRT6POLBMAPTLMNAMEN1
	SCHEMBL1126465	0.78	HTR3E (0.63)	HTR3EHTR3BHTR3AHTR3DHTR3C
	SCHEMBL1646189	0.77	MEN1 (0.61)	SIRT6POLBMAPTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.