Sulfaperin

Sulfaperin

SCHEMBL7944543

C1CCC1.Cc1cnc(NS(=O)(=O)c2ccc(N)cc2)nc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.65
TSHR P16473 2/20 0.62
AURKA O14965 1/20 0.62
DHFR P00374 1/20 0.62
ALDH1A1 P00352 5/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
CYP3A4 P08684 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
MAPT P10636 3/20 0.57
CYP2C9 P11712 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.55
EDNRA P25101 2/20 0.50
ADRA1A P35348 2/20 0.48
CYP2C19 P33261 2/20 0.47
PDE4A P27815 1/20 0.47
AGO2 Q9UKV8 1/20 0.47
HTT P42858 1/20 0.47
HSD17B10 Q99714 1/20 0.47
MEN1 O00255 1/20 0.47
EDNRB P24530 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfaperin SCHEMBL151755 0.95 LMNA (0.70) LMNATSHRAURKADHFRALDH1A1
Sulfaperin SCHEMBL9418724 0.94 LMNA (0.68) LMNATSHRAURKADHFRALDH1A1
Sulfaperin SCHEMBL16416441 0.94 LMNA (0.68) LMNATSHRAURKADHFRALDH1A1
Sulfaperin SCHEMBL9842258 0.82 LMNA (0.76) LMNATSHRAURKADHFRALDH1A1
SCHEMBL11267052 0.80 LMNA (0.67) LMNATSHRAURKADHFRALDH1A1
Sulfamethoxypyridazine SCHEMBL28086651 0.80 LMNA (0.77) LMNATSHRAURKADHFRALDH1A1
SCHEMBL6046849 0.80 LMNA (0.68) LMNATSHRAURKADHFRALDH1A1
SCHEMBL21753108 0.79 TSHR (0.60) LMNATSHRALDH1A1SMN1; SMN2TDP1
Sulfameter SCHEMBL79417 0.79 LMNA (1.00) LMNATSHRAURKADHFRALDH1A1
Sulfameter SCHEMBL17593237 0.78 LMNA (0.97) LMNATSHRAURKADHFRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6288262-B2 REACTION OF PHENOL WITH 2-CHLOROETHYL METHYL ETHER WITHOUT POLAR SOLVENT BAYER AKTIENGESELLSCHAFT (DE) 2001-09-11 US disclosed
US-20010014697-A1 Process for the preparation of 2-methoxyethoxy-benzenes and novel 2-methoxyethoxy-benzyl cyanides LANXESS DEUTSCHLAND GMBH (DE) 2001-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010014697-A1 Process for the preparation of 2-methoxyethoxy-benzenes and novel 2-methoxyethoxy-benzyl cyanides TET2, CYCS, TYR LMNA 1801/4885TSHR 4654/4885AURKA 2201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.