SCHEMBL1126735

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1993407	0.93	KDM4E (0.35)	MAPTALDH1A1LMNAHTR1ADRD2
	SCHEMBL942200	0.90	CASR (0.35)	CASREPHX2MAPTALDH1A1LMNA
	SCHEMBL1989932	0.87	LMNA (0.32)	CASRMAPTALDH1A1LMNAUSP2
	SCHEMBL942444	0.83	TRPV1 (0.33)	MAPTALDH1A1LMNAHTTMAPK1
	SCHEMBL1126695	0.81	NPY2R (0.41)	MAPTALDH1A1LMNAUSP2HTT
	SCHEMBL1126444	0.80	NPC1 (0.41)	MAPTALDH1A1LMNAHTTNPC1
	SCHEMBL30234686	0.80	MAPT (0.37)	MAPTALDH1A1LMNAUSP2HTT
	SCHEMBL1127148	0.80	MAPT (0.37)	MAPTALDH1A1LMNAUSP2HTT
	SCHEMBL30234731	0.78	MAPT (0.42)	MAPTALDH1A1LMNAUSP2HTT
	SCHEMBL1127284	0.78	MAPT (0.42)	MAPTALDH1A1LMNAUSP2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.