Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2A | P48426 | 2/20 | 0.38 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 13/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262913 | 0.86 | ALDH1A1 (0.39) | SELPLGCYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL11259590 | 0.84 | TRPV1 (0.37) | PIP4K2ASELPLGCYP3A4TRPV1ALDH1A1 | |
| SCHEMBL11261678 | 0.74 | TDP1 (0.45) | CYP3A4TRPV1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL11263009 | 0.73 | PIK3CA (0.35) | PIP4K2ATRPV1ALDH1A1 | |
| SCHEMBL11256929 | 0.73 | RAB9A (0.40) | CYP3A4TRPV1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL11257836 | 0.72 | BCHE (0.41) | DHODH | |
| SCHEMBL11255431 | 0.72 | SELPLG (0.44) | SELPLGCYP3A4TRPV1CYP2C9DHODH | |
| SCHEMBL20520340 | 0.71 | PPARG (0.49) | ALDH1A1 | |
| SCHEMBL11249519 | 0.71 | NPC1 (0.43) | CYP3A4TRPV1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL11253329 | 0.70 | TRPV1 (0.44) | CYP3A4TRPV1ALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |