SCHEMBL1126839

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126880	0.83	CNR2 (0.48)	ALDH1A1KDM4EMAPTPOLBKMT2A
	SCHEMBL1126957	0.82	ALDH1A1 (0.50)	ALDH1A1KDM4EMAPTPOLBL3MBTL1
	SCHEMBL1126875	0.80	MEN1 (0.51)	ALDH1A1MAPTPTGS2KMT2AMEN1
	SCHEMBL1126585	0.79	BRD4 (0.42)	ALDH1A1KDM4EMAPTL3MBTL1KMT2A
	SCHEMBL1126676	0.79	BRD4 (0.39)	ALDH1A1KDM4EMAPTL3MBTL1HPGD
	SCHEMBL1126694	0.79	BRD4 (0.42)	ALDH1A1KDM4ELMNABRD4PTGS1
	SCHEMBL1126926	0.77	SLC18A3 (0.43)	ALDH1A1KDM4ERECQLHPGDBRD4
	SCHEMBL1126684	0.77	KDM4E (0.50)	KDM4EL3MBTL1
	SCHEMBL1126929	0.76	TYR (0.46)	ALDH1A1KDM4EBRD4TSHRGAA
	SCHEMBL1126628	0.76	CCNC (0.46)	L3MBTL1HPGDBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.