SCHEMBL1126880

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126957	0.86	ALDH1A1 (0.50)	KDM4ESMN1; SMN2GAACYP1A2CYP2C19
	SCHEMBL1126875	0.84	MEN1 (0.51)	CYP1A2CYP2C19ALDH1A1KMT2AMEN1
	SCHEMBL1126839	0.83	ALDH1A1 (0.46)	KDM4ESMN1; SMN2GAAALDH1A1KMT2A
	SCHEMBL1127844	0.80	KDM4E (0.41)	CNR2KDM4ESMN1; SMN2GAACYP1A2
	SCHEMBL1126707	0.77	BRD4 (0.42)	KDM4EGAACYP2C19ALDH1A1HPGD
	SCHEMBL28590805	0.75	KDM4E (0.46)	KDM4ESMN1; SMN2GAACYP1A2CYP2C19
	SCHEMBL1126684	0.75	KDM4E (0.50)	KDM4E
	SCHEMBL1126926	0.75	SLC18A3 (0.43)	CNR2KDM4ESMN1; SMN2CYP1A2CYP2C19
	SCHEMBL1126585	0.74	BRD4 (0.42)	KDM4ESMN1; SMN2GAAALDH1A1KMT2A
	SCHEMBL1127344	0.74	MEN1 (0.42)	CNR2KDM4ESMN1; SMN2CYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.