Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259340 | 0.81 | KMT2A (0.41) | CYP3A4CYP2C19KMT2AMAPTMEN1 | |
| SCHEMBL11260852 | 0.76 | OPRM1 (0.46) | CYP2C19KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL11249228 | 0.71 | ALDH1A1 (0.39) | CYP3A4CYP2C19KMT2AMAPTALDH1A1 | |
| SCHEMBL11256659 | 0.71 | SMN1; SMN2 (0.45) | CYP3A4CYP2C19KMT2AMAPTMEN1 | |
| SCHEMBL11262496 | 0.69 | MAOB (0.45) | KMT2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL3697021 | 0.68 | CASP1 (0.45) | CYP2C19KMT2AALDH1A1CYP2D6 | |
| SCHEMBL11393611 | 0.68 | ALDH1A1 (0.36) | CYP3A4CYP2C19KMT2AALDH1A1LMNA | |
| Ozone SCHEMBL11388736 | 0.68 | ALDH1A1 (0.36) | CYP3A4CYP2C19KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11265307 | 0.68 | ALDH1A1 (0.36) | CYP3A4CYP2C19KMT2AALDH1A1LMNA | |
| SCHEMBL11337546 | 0.67 | KMT2A (0.40) | CYP3A4KMT2AMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360520-A | 1,4-Dihydropyridazine compounds, and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-23 | — | — | US | disclosed |