SCHEMBL1127152

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1127203	0.86	NPY2R (0.44)	MAPTNPSR1ALDH1A1POLBLMNA
	SCHEMBL1126696	0.86	MAPT (0.50)	MAPTNPSR1KDM4EALDH1A1POLB
	SCHEMBL1126487	0.85	MAPT (0.51)	MAPTNPSR1ALDH1A1POLBLMNA
	SCHEMBL1127109	0.83	MAPT (0.52)	MAPTNPSR1ALDH1A1LMNAMEN1
	SCHEMBL1126664	0.83	NPY2R (0.45)	NAMPTMAPTNPSR1ALDH1A1POLB
	SCHEMBL1992485	0.82	ALDH1A1 (0.48)	MAPTNPSR1KDM4EALDH1A1LMNA
	SCHEMBL19661313	0.82	GAA (0.42)	MAPTNPSR1ALDH1A1POLBLMNA
	SCHEMBL30235329	0.82	ALDH1A1 (0.48)	MAPTNPSR1KDM4EALDH1A1LMNA
	SCHEMBL1991472	0.81	KCNH2 (0.44)	MAPTNPSR1KDM4EALDH1A1POLB
	SCHEMBL1126909	0.81	MEN1 (0.41)	MAPTNPSR1ALDH1A1POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.