SCHEMBL1127203

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1127152	0.86	NAMPT (0.53)	NPC1RAB9AALDH1A1MAPTPOLB
	SCHEMBL1126664	0.86	NPY2R (0.45)	NPY2RNPC1RAB9AGAAALDH1A1
	SCHEMBL1126696	0.86	MAPT (0.50)	NPC1RAB9AGAAALDH1A1MAPT
	SCHEMBL1126487	0.85	MAPT (0.51)	NPC1RAB9AGAAALDH1A1MAPT
	SCHEMBL1127163	0.83	MAPT (0.41)	NPY2RNPC1RAB9AGAAALDH1A1
	SCHEMBL1127109	0.83	MAPT (0.52)	NPC1RAB9AGAAALDH1A1MAPT
	SCHEMBL1992485	0.82	ALDH1A1 (0.48)	GAAALDH1A1MAPTHSD17B10NPSR1
	SCHEMBL19661313	0.82	GAA (0.42)	NPC1RAB9AGAAALDH1A1MAPT
	SCHEMBL30235329	0.82	ALDH1A1 (0.48)	GAAALDH1A1MAPTHSD17B10NPSR1
	SCHEMBL1126909	0.81	MEN1 (0.41)	NPY2RNPC1RAB9AGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.