SCHEMBL1127109

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126696	0.86	MAPT (0.50)	MAPTALDH1A1HTTL3MBTL1MAPK1
	SCHEMBL1126487	0.85	MAPT (0.51)	MAPTALDH1A1HTTMAPK1TSHR
	SCHEMBL1126649	0.84	ALDH1A1 (0.43)	MAPTALDH1A1HTTTSHRLMNA
	SCHEMBL1126909	0.83	MEN1 (0.41)	MAPTALDH1A1HTTTSHRLMNA
	SCHEMBL1127203	0.83	NPY2R (0.44)	MAPTALDH1A1HTTLMNANPSR1
	SCHEMBL1127152	0.83	NAMPT (0.53)	MAPTALDH1A1MAPK1LMNASMN1; SMN2
	SCHEMBL1992485	0.82	ALDH1A1 (0.48)	MAPTALDH1A1HTTMAPK1TSHR
	SCHEMBL19661313	0.82	GAA (0.42)	MAPTALDH1A1HTTATMLMNA
	SCHEMBL30235329	0.82	ALDH1A1 (0.48)	MAPTALDH1A1HTTMAPK1TSHR
	SCHEMBL943058	0.81	MAPT (0.46)	MAPTALDH1A1HTTATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.