SCHEMBL1127040

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126844	0.89	KDM4E (0.46)	ALDH1A1POLBHTTBRD4KDM4E
	SCHEMBL1127469	0.86	BRD4 (0.38)	ALDH1A1BRD4KDM4ERAB9AMAPK1
	SCHEMBL1126929	0.84	TYR (0.46)	ALDH1A1BRD4KDM4ETSHRTYR
	SCHEMBL1126990	0.83	CNR1 (0.45)	ALDH1A1BRD4KDM4ETSHRCNR1
	SCHEMBL1127094	0.81	TYR (0.49)	ALDH1A1BRD4KDM4ERAB9ATSHR
	SCHEMBL1126944	0.81	KDM4E (0.41)	BRD4KDM4ERAB9AMAPK1TYR
	SCHEMBL1127015	0.80	RAB9A (0.49)	ALDH1A1RAB9AMAPK1TSHRMAPT
	SCHEMBL1127357	0.79	BRD4 (0.37)	ALDH1A1BRD4KDM4ERAB9ACNR1
	SCHEMBL1126608	0.78	ALDH1A1 (0.39)	ALDH1A1POLBBRD4RAB9AMAPK1
	SCHEMBL1127089	0.77	GLO1 (0.42)	ALDH1A1BRD4RAB9AMAPK1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.