Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126940 | 0.86 | KDM4E (0.40) | ALDH1A1HPGDCYP2C19MEN1KMT2A | |
| SCHEMBL16500197 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MAPTHPGDDHODHCYP1A2 | |
| SCHEMBL26112712 | 0.69 | ALDH1A1 (0.48) | ADORA3ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL1126998 | 0.69 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDHSD17B10CYP1A2 | |
| SCHEMBL11227110 | 0.68 | LMNA (0.57) | ALDH1A1MAPTHSD17B10DHODHMEN1 | |
| SCHEMBL1126782 | 0.67 | ALDH1A1 (0.51) | ADORA3ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL27944221 | 0.67 | ADRB2 (0.34) | ADORA3ALDH1A1HPGDPDE3BPDE3A | |
| SCHEMBL27944223 | 0.67 | ADRB2 (0.34) | ADORA3ALDH1A1HPGDPDE3BPDE3A | |
| SCHEMBL3344995 | 0.66 | TUBB4A (0.53) | ADORA3ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL28462587 | 0.66 | HDAC7 (0.56) | ALDH1A1MAPTHPGDHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |