Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ITK | Q08881 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127001 | 0.86 | ADORA3 (0.39) | HCAR2L3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL27944221 | 0.71 | ADRB2 (0.34) | KDM4EHCAR2SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL27944223 | 0.71 | ADRB2 (0.34) | KDM4EHCAR2SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL27828702 | 0.65 | EGFR (0.54) | KDM4EGAAALDH1A1EGFR | |
| SCHEMBL1127401 | 0.64 | CD274 (0.33) | GAAMEN1KMT2ATSHRCYP2C19 | |
| SCHEMBL28025320 | 0.63 | ADRB2 (0.39) | KDM4EHCAR2L3MBTL1GAATSHR | |
| SCHEMBL792179 | 0.62 | DPP4 (0.50) | KDM4EL3MBTL1GAAKMT2APTGER2 | |
| SCHEMBL28566574 | 0.62 | LOXL2 (0.55) | — | |
| SCHEMBL7260927 | 0.62 | LOXL2 (0.58) | KDM4EGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2375007 | 0.62 | L3MBTL1 (0.54) | HCAR2L3MBTL1GAASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |